How Long After Prolia Injection Do Side Effects Start? | A Patient Guide
Prolia (denosumab) has become a widely used treatment for osteoporosis because of its convenience — only one injection every six months — and its proven ability to strengthen bones and reduce fracture risk. But if you’re considering or already taking Prolia, you may be asking: How long after a Prolia injection do side effects start? Let’s break it down so you know what to expect. What Is Prolia and How Does It Work? Prolia is a prescription medication used to treat osteoporosis in postmenopausal women, men at high risk of fracture, and some prostate cancer patients who experience bone loss due to therapy. It works by blocking a protein called RANKL, which normally helps break down bone tissue. By inhibiting this process, Prolia: Slows bone loss Increases bone density in the spine, hip, and thigh bone Reduces the risk of fractures Unlike daily pills, Prolia is injected just twice a year, making it a convenient option for long-term bone health. How Long After Prolia Injection Do Si...